Gary D. Stoner
THE OHIO STATE UNIVERSITY
Gary Stoner has expertise in the fields of chemical carcinogenesis and cancer chemoprevention. Early studies in his career were focused on lung cancer and tobacco carcinogenesis. Later, his laboratory conducted research on the identification of naturally-occurring compounds to prevent cancer including ellagic acid and a series of isothiocyanate compounds that were exquisite inhibitors of lung and esophageal cancer induced by N-nitrosamine carcinogens. More recently, his laboratory pioneered a “food-based” approach to cancer prevention using freeze-dried black raspberries. Initially, the berries were found to inhibit chemically-induced cancer in the rodent oral cavity, esophagus, colon and skin through reducing cell proliferation, inflammation, angiogenesis and stimulating apoptosis. In humans, the berries were found to cause partial to total regression of premalignant lesions in the oral cavity, esophagus and colon. He will discuss the results of his studies in his presentation.
chemical carcinogenesis and cancer chemoprevention