Day 1 :
Keynote Forum
Marcello Menapace
M&Ms Consulting Ltd., UK
Keynote: Physical and genetic constitution: A new biotype synthesis
Time : 11:20-12:05
Biography:
Marcello Menapace is a researcher, philosopher, scientist, medical writer, and professional regulatory consultant. He has worked in the pharmaceutical industry
for over 15 years as a lead consultant and research scientist for various biotech Companies and is a member of the professional organization TOPRA. He is
the director of M&Ms Consulting Ltd, a high-end consultancy service organization, He has completed his first Master’s degree at the University of Milan (IT) in
Chemistry, his second Master’s degree in Business Administration (MBA) at the London School of Business and Finance in London (UK) and his PhD in Life
Science at the H. S. University in Philadelphia (US). He has published 1 scientific paper on Science and Ethics, will be honourable speaker at the European
Congress of Applied Science and is currently collaborating with Biotech Companies to publish other biological and chemical research manuscripts.
Abstract:
Statement of the Problem: Historically, medicine has always looked at humanity as distinguished in various constitutional
types. Constitutional Medicine, with its tenets, was the main form of Western medicine until the 1950s, is now
included in more modern forms of medicine such as Evolutionary medicine and is the basis of all non-Western (Eastern)
medicines: Unani, TCM, Ayurveda, etc. While the number of somatotypes varies according to tradition, the fundamental
concepts remain the same. On this basis, dietary recommendations have been developed for each body type, in the past
as in the present. In the 1920s a new division of humanity has opened the doors to modern chemical testing: the ABO
blood type. Women and men are divided into four blood groups: A, B, AB and O. The blood type diet has risen from this
division and spread worldwide. It is herewith proposed a new synthesis between these two biotypologies. The Western
biotype classification has been used for simplicity and for traditional purposes. As per all currently known constitutional
medicines, dietary advices are tailored to the physical constitution and now, with the ABO grouping, also to genetic
constitution (biochemical determinants). The result is a new nutritional system, which takes into account both the welltested
traditional suggestions (seasonal foods, etc) and the contemporary biological medicine. Food, as in all Oriental and
traditional medicines, becomes the primary treatment for ailments and for the maintenance of health. The new system
will be reviewed in light of recent advances in nutritional sciences.
- Nutrition and Health | Pediatric and Maternal Nutrition | Nutritional Science | Food Microbiology
Location: SESSION
Session Introduction
Emil K. Mukhamejanov
Fucoidan World, Kazakhstan
Title: Obesity and protein exchange
Time : 12:05-12:35
Biography:
Emil Mukhamejanov is a doctor of medical sciences, professor. In 1964-1972, I worked in the Institute of Physiology, responsible for the regulation of muscle
contraction. In 1974-1991, I worked in the Institute of nutrition, responsible for the regulation of energy metabolism and metabolic diseases. Developed metabolic
model of balanced diet coupled with effects of toxic compounds, physical activity and dietary factors. Has developed specialized nutrition products for athletes
and for the prevention and treatment of metabolic diseases. Currently working in the Scientific Center of anti-infective disorders, develop approaches of reducing
the negative impact of drugs. I participate in a grant (JSC National Medical University named after S.Asfendiarov) for the study of polymorphism in diabetes
mellitus. I am a scientific consultant at Fucoidan-World.
Abstract:
Objective: The body has a number of idle energy-dependent metabolic cycles that contribute to the conservation of
energy balance. The protein turnover increases with excess intake of calories and decreases with their deficiency, so
it can contribute to maintaining the energy balance.
Methods: The approach was to develop a model for establishing the key role of protein metabolism in coordinating
the metabolism of carbohydrates and fats.
Results: There was developed a model for the relationship between proteins, fats and carbohydrates exchange. In
the absorptive period, a decrease in protein synthesis with a protein deficit (low protein diet) leads to a reduction in
glucose utilization, which is manifested by its increase in blood and an increase in the discharge of its carbon skeleton
into lipids. On the contrary, on the high-protein diet the negative manifestations of the restriction of physical activity
on the exchange of glucose and fats are smoothed out. In the post-absorptive period, proteins are the main supplier
of the substrate for the process of gluconeogenesis, which is provided by the energy of fat oxidation, so fat oxidation
increases on the high protein nutrition. This allowed us to offer a product for obesity diet therapy (Patent GB496119
January 22, 2014).
Conclusion: Thus, protein metabolism plays a coordinating role in the mechanism of carbohydrate and fat
metabolism, and in order to increase the effectiveness of technology in the prevention and treatment of obesity,
adequate substrate support of the protein synthesis process (quantity and quality).
Flaminia Cesare Marincola
University of Cagliari, Cagliari, Italy
Title: Metabolomics in the nutrition of infant
Biography:
Metabolomics is one of the most recent omics sciences that refers to comprehensive measurement of the pool
of small molecules called metabolome present in a biological sample. It is in the downstream end of the postgenomic
technologies and it allows investigating the metabolic status of an organism in relation to the genome
interaction with environmental factors such as drug treatment, diet, lifestyle, and environmental agents. Being
able to provide a dynamic picture of the functionality (i.e., of the phenotype) of a biological system, metabolomics
is having a significant impact on many fields of research. One of these is nutrition science for which the word
nutrimetabolomics or nutritional metabolomics has been coined. Here metabolomics is basically use to study
relationships between food and health, with particular focus on the identification of new dietary biomarkers, the
study of diet-related diseases and the application to intervention studies to understand the potential role of the diet
in health promotion (personalized medicine)Nutrimetabolomics appears to be a promising technique also in the
pediatric and neonatal field where research is focusing more and more on preventing the development of long-term
diseases as well as supporting the repair processes important in the therapy of already fully developed diseases.
Most children who are hospitalized or affected by chronic diseases could benefit from specific and careful attention
to nutrition. Indeed, there is a growing recognition that the nutritional status of infants has profound implications
not only for their health and growth but also for the development of the health and future of all individuals. The
purpose of this presentation is to provide an overview of the applications of metabolomics technology in the context
of neonatology and pediatrics with emphasis on the potential applications of this approach in the area of nutrition.
Abstract:
Flaminia Cesare Marincola is currently associate professor in the Department of Chemical and Geological Sciences at the University of Cagliari, Italy. She has
her expertise in using Nuclear Magnetic Resonance (NMR) spectroscopy for the characterization of biological systems. In the last 10 years, her research has
mainly been carried out in the metabolomics field, performing studies of interests in both the area of neonatology and food science. She is the author of 60
publications in international journals and 6 book chapters.